pytorch
Affinity Groups
There are no Affinity Groups associated with this topic. View All Affinity Groups.
Announcements
| Title | Date |
|---|---|
| CI Pathways: Leading the Way to Effective CI Use | 02/20/25 |
| Ookami Webinar | 02/14/24 |
Upcoming Events & Trainings
| Title | Date |
|---|---|
| CI Pathways: Multi-GPU Training with Accelerate | 4/22/25 |
| NAIRR Pilot Office Hours | 5/13/25 |
| NAIRR Pilot Office Hours | 6/10/25 |
Topics from Ask.CI
Loading topics from Ask.CI ...
Knowledge Base Resources
| Title | Category | Tags | Skill Level |
|---|---|---|---|
| Attention, Transformers, and LLMs: a hands-on introduction in Pytorch | Learning | ai, deep-learning, machine-learning, neural-networks, pytorch | Intermediate |
| DeepChem | Tool | pytorch, tensorflow, computational-chemistry | Beginner, Intermediate, Advanced |
| fast.ai | Website | ai, machine-learning, pytorch, training | Beginner, Intermediate, Advanced |
Engagements
Re-engineering Lilly’s KisunlaTM into a novel antibody targeting IL13RA2 against GBM using AI-driven macromolecular modeling
Atrium Health Levine Cancer
- Summary and objectives of the proposed experiments:
- An initial research-based Ab (scFv47, discovered by our collaborator Dr. Balyasnikova) model, modeling Ab-Ag (IL13RA2 against GBM) protein complex, and identifying the binding sites (epitopes) using ROSETTA and AlphaFold2 multimer tools.
- Graft the CDRs of scFv (single-chain variable fragment) of antibody or Bispecific T cell engagers (BTEs) onto the template Ab, the framework of Lilly's Kisunla™ Ab drug.
- Modify, improve, and optimize the overall or full antibody protein structures using AI-driven macromolecule modeling (AlphaFold3).
- Explore single nucleotide polymorphism (SNP), pathogenic genetic variants and N-glycosylation of IL13RA2 (target) protein domain interacting with the Ab candidates among the patient population using ROSETTA software packages.
Status: In Progress
People with Expertise
alex Gutierrez
California State University-Los Angeles
Programs
ACCESS CSSN
Roles
student-facilitator
Expertise
William Lai
Cornell University
Programs
ACCESS CSSN
Roles
mentor, researcher/educator, research computing facilitator, research software engineer, ci systems engineer, Consultant
Expertise
Rebecca Belshe
Arizona State University
Programs
Campus Champions, CCMNet
Roles
research computing facilitator, CCMNet
Expertise
People with Interest
Parameshwaran Pasupathy
Rutgers, the State University of New Jersey
Programs
ACCESS CSSN, CAREERS
Roles
student-facilitator
Interests
Shawn Sivy
The College of New Jersey
Programs
Campus Champions, CAREERS
Roles
research computing facilitator, ci systems engineer
Interests
Bala Desinghu
Harvard University
Programs
ACCESS CSSN, Campus Champions, CAREERS, Northeast
Roles
mentor, researcher/educator, research computing facilitator, cssn, Consultant
